CALL FOR ACTION PLAN FOR PATIENTS WITH CHRONIC KIDNEY DISEASE
European Alliance for Kidney Health points to major deficits


03/03/2022 - The European Kidney Health Alliance (EKHA) has called for significantly more efforts to combat chronic kidney disease (CKD) in the European Union (EU) and a European action plan.


In Europe, 100 million people suffer from CKD. Of these patients, at least 10% have a rare kidney disease for which there is no specific treatment. It is estimated that CKD will be the fifth leading cause of death worldwide by 2040. However, CKD is also a cost factor. The total costs are at least as high or even higher compared to cancer and diabetes. Haemodialysis in centres is the most common treatment option, although it incurs the highest costs. To improve the situation in the long term, EKHA recommends the following measures:


1. Better prevention of CKD and, in the case of existing CKD, best possible delay of progression.


The aim here is to reduce or avoid lifestyle-related risk factors such as smoking, alcohol consumption, unhealthy diet, lack of exercise, obesity, high blood pressure and diabetes. Screening should be promoted for high-risk groups. 


2. Improved access to treatment and intensification of therapy research 


Kidney transplantation is the best treatment option compared to dialysis in terms of life expectancy, quality of life and cost. 


For patients who cannot be transplanted, home dialysis is more beneficial than centre dialysis. However, access to these options varies across the EU, leading to inequalities in care. In particular, there are deficits in Central and Eastern Europe. Furthermore, the treatment of kidney failure has not changed significantly in the last 50 years and remains very burdensome for patients. There has been no comparable progress as with cancer, HIV, cardiovascular disease or diabetes.


In contrast to the US, there is little commitment and funding in Europe to support encouraging approaches such as mobile or implantable artificial kidneys or xenotransplantation.

Recommendations

  • Optimise organ donation and transplantation and access to home dialysis (EU4Health programme) and strengthen cooperation between national authorities,
  • Prioritise research into more innovative CKD treatments through the Horizon Europe programme and the Innovative Health Initiative (IHI),
  • Contribute to improvement the care of patients outside Europe, particulary in Africa, the Caribbean and the Pacific.


3. Better awareness of the particular vulnerability and burden of patients in the pandemic.


Patients with CKD are particularly affected by COVID-19. Mortality rates in COVID-19 patients are worrying: 20% in kidney transplant patients and 21% in dialysis patients. Moreover, vaccine efficacy is very low, especially in transplant patients. Moreover, the risks, isolation and sometimes vague recommendations of the authorities have severely affected the social, family and professional lives as well as the mental health of people with kidney disease. perception of the special risk and burden on patients in the pandemic

Recommendations

  • More attention to the special situation of people with kidney disease in the fight against COVID-19 and future pandemics,
  • More research on vaccine boosting and preventive or therapeutic treatments for kidney disease ("Horizon Europe"),
  • More cooperation between Member States


4. Promotion of "green dialysis"

All CKD treatments have a considerable carbon footprint and cause a significant environmental impact. In addition, dialysis generates a lot of plastic waste and uses huge amounts of water, more than 169 billion liters per year worldwide.

Recommendations

  • Promotion of organ transplantation, a more efficient treatment that is also significantly less polluting than dialysis,
  • Funding of European projects, in particular "Horizon Europe" and "LIFE 2021-2027", to develop more environmentally friendly dialysis equipment,
  • Greater prevention, to reduce the incidence of CKD and thus reduce the use of environmentally harmful treatments such as dialysis.
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